Pan-Cancer Targeted Sequencing Panels

Pan-Cancer Panel

The Pan-Cancer CancerScreen Targeted Sequencing Panels from Celemics are NGS assays designed to detect all types of variants in over 400 genes associated with somatic cancer. The panels target the selected genes with high sensitivity and specificity, reducing costs and minimising time and resource. The reports consists of the primary, secondary, and tertiary results for the in-depth understanding and interpretation of sequencing data.

Highly Comprehensive and Optimised Targeted NGS Panels for Solid Cancers

• Identifies mutations implicated in various somatic cancers, e.g. breast, colorectal, gastric, liver cancer, etc.
• Assess DNA, RNA, and the whole CDS regions (RefSeq) of up to 407 genes and rearrangement regions associated with solid cancer

High Sensitivity and Specificity

• Detect low-frequency and rare variants with high sequencing depths
• Capture the GC rich and homologous regions with Celemics proprietary design technology

Immunotherapy Biomarkers Analysis

• Assess all variant types: detect all mutation types including SNV, Indel, Large Indel, CNV, Rearrangement, microsatellite instability (MSI), and Tumour Mutation Burden (TMB) in a single assay

Industry-Leading Performance

• The Pan-Cancer CancerScreen Targeted Sequencing Panels provide even higher target enrichment efficiency when compared to the same target regions of competing panels.

Extensive validation studies

• Robust panel performance supported by extensive validation tests with reference and clinical specimens

CancerScreen Panel Specification

* Gene Add-on Service: Genes can be added or removed by customer demand

Package Composition

Performance Comparison with Competitor’s Pan-Cancer Targeted Sequencing Panel

Celemics’ Pan-Cancer CancerScreen Targeted Sequencing Panels deliver higher on-target ratio, uniformity, and coverage at 100X compared to  competitors product over the target regions including exons and introns (compared with the same sequencing depth).

Performance Comparison over GC-rich Regions

Higher uniform read depths over GC-rich regions compared to competitor product (Compared with the same sequencing depth)

Contact VH Bio to learn more about the Pan-Cancer Targeted Sequencing Panels or view the product range below.