Find Products

QuantideX® NGS RNA Lung Cancer Kit

The QuantideX® NGS RNA Lung Cancer Kit* is a clinical research tool enabling the simultaneous assessment of fusions, exon skipping, and other expression targets frequently observed in non-small cell lung cancer (NSCLC). Leveraging Asuragen’s proprietary NGS-in-a-Box™ workflow and Sample-Aware™ bioinformatics quality control solutions, this kit offers a simple, sensitive, and reliable NGS assay for routine […]

The QuantideX® NGS RNA Lung Cancer Kit* is a clinical research tool enabling the simultaneous assessment of fusions, exon skipping, and other expression targets frequently observed in non-small cell lung cancer (NSCLC). Leveraging Asuragen’s proprietary NGS-in-a-Box™ workflow and Sample-Aware™ bioinformatics quality control solutions, this kit offers a simple, sensitive, and reliable NGS assay for routine investigation of NSCLC samples.

Features & Benefits

The QuantideX NGS RNA Lung Cancer Kit offers a unique NGS-in-a-Box™ solution that provides unprecedented NGS workflow efficiency and high sensitivity at low input amounts from precious FFPE NSCLC samples.

Reduced Complexity | Assay incorporates sample-to-data solutions in a unique NGS-in-a-Box™ configuration

  • Single assay for a broad range of important NSCLC fusion targets
  • All-inclusive reagents from reverse transcription to NGS-ready library
  • Fully integrated data analysis pipeline

Optimized Workflow | Efficient workflow leads to lower operational costs and reduced hands-on and total turnaround time*

  • Reduced labor vs. current commercially available kits
  • Improved turnaround time enables higher throughput

Quality Performance | Highly sensitive assay with integrated, Sample-Aware™ bioinformatics software and built-in quality checks to minimize erroneous results and sample failures

  • Highly sensitive detection of RNA-based fusions
  • Low input (~20ng) of RNA from FFPE
  • Sample-Aware™ bioinformatics analysis and sample quality control

Relevant Content | A focus on only the most important lung cancer fusion genes, MET exon 14 skipping events, 3’/5′ imbalances and mRNA expression from multiple published data sources such as COSMIC, ClinicalTrials.gov, NCCN Guidelines, etc.

  • 107 NSCLC-relevant fusions
  • ALK, RET, ROS1, NTRK1 & PDGFRA 3’/5’ imbalances
  • MET exon 14 skipping events (e13/e14; e14/e15; e13/e15)
  • 23 mRNA targets, plus 3 endogenous control transcripts

A Fully Integrated Workflow | A unique NGS-in-a-Box™ configuration offers a simplified and fully integrated NGS workflow with cGMP-manufactured reagents, components and controls ready to run right out of the box.
Includes:

  • RT-PCR reagents
  • A unique RNA Lung Cancer Sample QC kit (QuantideX qPCR RNA Assay (Lung))
  • Gene-specific PCR primers and Master Mix reagents
  • Barcodes for sample multiplexing
  • Library purification and quantification reagents
  • Integrated data analysis and reporting software (QuantideX NGS Reporter)

 

 

Rapid & Efficient | Adopt and run NGS-based analysis with minimum investment of time and resources, regardless of NGS experience and infrastructure.

  • Fully integrated workflow reduces complexity and ensures reliable reagent quality
  • Push-button analysis & reporting makes bioinformatics easy and efficient, regardless of experience level
  • Integrated kit reduces workflow time by over 50% than competing NGS panels

 

 

Performance Data | QuantideX NGS Assay is capable of detecting fusions and splice variants down to 1:100 cells. (a) Admixture of MET exon 14 positive cell line in the background of wild-type cells, and (b) fusion, and (c) 3’/5’ imbalance status for an admixture of EML4-ALK positive FFPE in the background of a negative FFPE.

 

Figure 3a

Figure 3b

Figure 3c

Push-button analytics & reporting suite | Set up and go workflow designed for easy installation and implementation, right out of the box.

Runs directly on lab desktop | Install locally on a standard Windows® desktop computer. No prior bioinformatics experience or large server environments required.

Comprehensive reporting | Full bioinformatics and reporting of variants (SNPs and indels), and standard QC metrics are automatically calculated.

Integrates QuantideX qPCR DNA QC Assay | “Sample-aware” bioinformatics that factor in functional template copy number, dramatically reducing false call rates.

Seamless updates offered with new panel designs & variant annotation | Software updates allow new panels to be adopted without re-investing in analytics when incorporating Asuragen QuantideX NGS panels.

*For Research Use Only. Not for use in Diagnostic procedures.

Read more +

View Products Enquire Now Additional Resources

Showing all 2 products

Filter by:

Product Units
QuantideX® NGS RNA Lung Cancer Kit
649602
48 Reactions
QuantideX® NGS RNA Lung Cancer Kit
649603
192 Reactions
  • Enquire Now

    We work with a range of suppliers with novel and innovative products sourced from our global partners.

  • This field is for validation purposes and should be left unchanged.

Additional Resources

Find Products

We work with a range of suppliers with novel and innovative products sourced from our global partners.

Find Products

Browser Warning

VHBio is not supported on Internet Explorer and will not provide you with the best experience. Please consider switching to a compatible browser such as Microsoft Edge, Google Chrome or Firefox.