Find Products

Help Us, Help You

We genuinely believe in what we do and want to be the best life sciences supply partner. Any information to help our journey is very welcome. Please take a few minutes to help us improve and make your future experiences better:

Quantidex® QPCR BCR-ABL IS Kit

The QuantideX BCR-ABL IS Kit provides labs with a robust and reliable method for monitoring leukaemia patients, also allowing them to keep pace with the advances in TKI therapy. Reduced Complexity | Ease-of-data analysis and reporting: Direct reporting on the International Scale (IS): No sample exchange or conversion factor calculations required Data analysis software eliminates manual […]

The QuantideX BCR-ABL IS Kit provides labs with a robust and reliable method for monitoring leukaemia patients, also allowing them to keep pace with the advances in TKI therapy.

Reduced Complexity | Ease-of-data analysis and reporting:

  • Direct reporting on the International Scale (IS): No sample exchange or conversion factor calculations required
  • Data analysis software eliminates manual intervention to provide automated calculations and streamlined reporting

Optimized Workflow | Valuable operator hands-on time has been significantly reduced through:

  • Multiplexed assay design that amplifies and detects both fusion and control gene in the same reaction
  • All-inclusive reagents sourced and Quality Controlled together from a single vendor
  • Pre-mixed tubes leading to fewer pipetting steps in the mastermix preparation

Quality Performance | Detecting BCR-ABL Transcripts robustly, reliably with a highly sensitive assay:

  • Sensitivity of MR4.7 (0.002%IS): 95% positivity at this LOD as determined by testing human RNA specimens
  • Increased sensitivity without compromising specificity: Non-CML (major) transcripts not detected by the assay
  • Armoured RNA based standards providing true RNA quantification for a quantitative RNA assay
  • Robust performance as indicated by minimum variability of replicate measurements

Analytical Characteristics

  • Proven sensitivity based on rigorous testing criterion (Figure 1)
  • Minimal variability across the entire dynamic range of % IS values (figure 2)
  • Multiplexed design leads to workflow and cost efficiency (figure 3)

Proven Sensitivity Based on Rigorous Testing Criterion

Figure 1 Probit_US_IVDweb

Figure 1: LOD as determined by CLSI EP-17A2 guidelines by testing Human RNA dilutions ranging from MR4.4 to MR6: 60 replicates of each dilution for a total of 1260 data points.
Minimal Variability Across Entire Dynamic Range of %IS Values

Minimal Variability Across Entire Dynamic Range of %IS Values

Table 1 BCRABL IS Kit

Figure 2. Precision was evaluated by using 5 different levels of positive specimen, tested by 3 operators over 20 runs. Each level was tested 40 times to obtain Standard Deviations.

Multiplexed Design Leads to Workflow and Cost Efficiency

Figure 3: Comparison of a plate layout for 8 sample run on Asuragen plate (left) and an alternate non-multiplex assay (right): 19 reactions for Asuragen set up vs 60-64 reaction on a non-multiplex assay set up

Read more +

View Products Enquire Now

Single product

Filter by:

Product Units
Quantidex® QPCR BCR-ABL IS Kit
686003
60 Reactions
  • Enquire Now

    We work with a range of suppliers with novel and innovative products sourced from our global partners.

Additional Resources

Find Products

We work with a range of suppliers with novel and innovative products sourced from our global partners.

Find Products

Browser Warning

VHBio is not supported on Internet Explorer and will not provide you with the best experience. Please consider switching to a compatible browser such as Microsoft Edge, Google Chrome or Firefox.