Respiratory Virus Targeted Sequencing Panels

Celemics’ Comprehensive Respiratory Virus Panel (CRVP) is a detection panel for the accurate sequencing and identification of prominent whole viral genomes, including coinfection possibilities such as COVID-19 and influenza.

One of today’s most harrowing public health issues is research into ways to fight viruses that are becoming increasingly more infectious and difficult to cure, especially clinically significant and prevalent respiratory viruses like coronavirus. The Comprehensive Respiratory Virus Panel (CRVP) from Celemics was developed using nine respiratory virus types and 39 strains in order to effectively detect and sequence respiratory disease-causing viruses in humans using the NCBI RefSeq database as its foundation.

Wide Spectrum of Respiratory Virus Species Coverage

The CRVP is an ideal tool for extensive research in the field of respiratory pathogens, including currently relevant viruses such as SARS-CoV-2 and Influenza A/B, along with virus types commonly researched in lab and clinical environments such as human rhinovirus A/B/C, respiratory syncytial virus, and parainfluenza virus. Each strain of virus type that the CRVP was designed for was based on their prevalence in human populations and referenced using the NCBI database.

Key benefits and features of the viral NGS panel:

Coverage of wide range of respiratory pathogens

• Testing of 39 strains for 9 different virus types

Double pandemic/coinfection detection

• Simultaneous testing of all relevant viral strains
• High 1X coverage levels to guarantee detection and whole genome capture

Inclusion of stand-alone BI analysis software, the Celemics Virus Verifier

• Deliverance of results in-house
• Guarantee security of client sequence information

Clear results even from low-quality clinical specimens

• Samples collected from several patient sites (upper respiratory tract, NP/OP swabs)

High detection sensitivity and consensus sequence generation rate

• Pathogen detection at as little as 100 copies
• >99% mean depth up to 100x coverage

One day workflow using hybridisation enhancer technology

Inclusion of all required kit components (RNA to cDNA, cDNA to captured library)

Table 1. Respiratory viral species and strains covered by CRVP

Table 2. Sample clinical samples coverage using CRVP

Contact VH Bio for more info or to place an order.