This product line is based on a proprietary platform technology which has enabled the creation of a series of immortalized hypothalamic neurons. Using CNTF (ciliary neurotrophic factor) to trigger neurogenesis, the cells were immortalized from two month old male (CLU170-CLU194) or two month old female (CLU450-CLU472) C57Bl/6 mice hypothalamic primary cultures by retroviral transfer of […]
This product line is based on a proprietary platform technology which has enabled the creation of a series of immortalized hypothalamic neurons. Using CNTF (ciliary neurotrophic factor) to trigger neurogenesis, the cells were immortalized from two month old male (CLU170-CLU194) or two month old female (CLU450-CLU472) C57Bl/6 mice hypothalamic primary cultures by retroviral transfer of SV40 T-Ag. These cell lines have been found to express an ever expanding array of neuropeptides, enzymatic markers and biologically active receptors. As such, these cell lines enable accurate in-vitro assays for use in the discovery, development and validation of new therapeutics targeted to central-nervous system diseases and disorders, including obesity, stress, and metabolic disorders, amongst others.
| Product | Units |
|---|---|
|
mHypoA-NPY/GFPmix CLU499 |
1 Ml |
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