MolYsis™

MolYsis™ is a pre-analytical tool serving the molecular detection of bacteraemia, fungemia and other infections. MolYsis constitutes a unique system for the targeted isolation of microbial DNA from clinical samples. By the selective lysis of human cells and the degradation of non-target human DNA, PCR analysis of pathogens is extremely enhanced through increased sensitivity and specificity.

The result of MolYsis pre-treatment with concomitant isolation of enriched pathogen DNA is an increase of the PCR analytical sensitivity of up to 40,000-fold compared to conventional total DNA isolation. Molzym offers whole blood pre-treatment kits, MolYsis™ Basic, MolYsis™ Basic5 and MolYsis™ Basic10 that can be combined with any microbial DNA isolation kit established in the laboratory, including manual and automated systems.

Pre-treatment and DNA isolation kits, MolYsis™ Complete5 and MolYsis™ Complete10 combine all pre-analytical components and procedures necessary for high sensitivity pathogen PCR analysis. Blood cultures can be extracted by MolYsis™ Plus providing highly pure pathogen DNA for PCR analysis.