Embryonic Rat Hypothalamic Cell Lines

This product line is based on a proprietary platform technology which has enabled the creation of a series of immortalized hypothalamic neurons; immortalized from rat embryonic day 18 hypothalamic primary cultures by retroviral transfer of SV40 T-Ag. These cell lines have been found to express an ever expanding array of neuropeptides, enzymatic markers and biologically active receptors.
As such, these cell lines enable accurate in-vitro assays for use in the discovery, development and validation of new therapeutics targeted to central-nervous system diseases and disorders, including obesity, stress, and metabolic disorders, amongst others.