Custom Antibody Development Services

Custom Antibody Services from Cedarlane®

VH Bio facilitates access to Cedarlane custom antibody development services for researchers and laboratories across the UK and Republic of Ireland, providing local support from initial enquiry through to project coordination. With over 30 years of experience, Cedarlane has successfully completed custom antibody projects for researchers, biotechnology manufacturers and pharmaceutical companies.

Each project begins by defining the customer’s requirements, intended application and project specifications. Cedarlane then develops a tailored project plan, with key stages and anticipated timelines communicated throughout the project. VH Bio acts as the local point of contact, helping to coordinate the enquiry and project requirements with Cedarlane.

• Comprehensive solutions. Custom antibody development, assay development, and diagnostic kit development.
• Expert support. Technical expertise and project coordination throughout the development process.
• ISO-certified quality. Quality-focused processes supporting reliable and confidential project delivery.
• Timely delivery. Cedarlane works to complete projects within the agreed timeframe, providing the high-quality custom antibody products customers have come to expect.

Polyclonal Antibody Development

Cedarlane offers complete polyclonal antibody development programmes, including immunogen selection and production, antibody production, purification, conjugation, testing and lyophilisation.

Host animals include:

• rabbits
• sheep
• goats
• mice
• rats
• guinea pigs
• ferrets
• llamas
• chickens

Please contact VH Bio to discuss options for additional host species.

Antigen sources include:

• peptides
• full or partial proteins
• cells
• lysates
• plant material

Monoclonal Antibody Production

Cedarlane can supply monoclonal antibodies as Cell Line Supernatants (in vitro products), or as Ascites fluid using BALB/c, nude or other strains of mice.

Production includes initial cell expansion, priming of the host, isotyping and cryopreservation of the cells if required. Low endotoxin antibody production and purification is also available.

Antibody Purification

Monoclonal and polyclonal antibodies can be purified by:

• Protein A/G chromatography
• Affinity chromatography
• Ammonium sulphate precipitation

Peptide Synthesis

All peptides are supplied with Mass Spectral analysis to confirm identity and HPLC chromatograms to assess purity.

Custom Antibody Conjugation

• Biotin, FITC, PE, Horseradish Peroxidase (HRP) and other labels
• Carrier protein conjugations (for polyclonal antibody production; BSA, KLH, OVA)

Other conjugation services available upon request.

Testing Services

Cedarlane can test samples using ELISA, Flow Cytometry, Western Blotting and Cytotoxicity assays.

Lyophilisation and Finished Formats

Material can be filled into specified vial sizes and supplied in an appropriate finished format according to project requirements.

Bulk Antibody Production

Cedarlane can also support projects requiring larger quantities of antibody, including bulk production and supply. Speak to VH Bio about anticipated volumes and project requirements so that appropriate production and pricing options can be discussed.

Speak to VH Bio to discuss your custom antibody requirements or find out more about Cedarlane’s custom antibody services.

Please fill in the form below to request a quote. Providing details such as your target or antigen, intended application, preferred host species, purification or conjugation requirements and anticipated quantity will help us work with Cedarlane to define the most appropriate approach and provide a project quotation.