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Sanger Sequencing in Diagnostic Labs

22 September 2023

The sequencing of single or multiple genes is often the first step in the genetic diagnosis of a disease and informs subsequent treatment and care. The development of the Sanger sequencing method in 1977 allowed labs to sequence DNA fragments with automated base calls for the first time. While continual developments have led to innovative technologies such as Next Generation Sequencing (NGS), Sanger sequencing is still considered the gold standard technique for some clinical scenarios, for example, 16S sequencing, human leukocyte antigen (HLA) typing, microsatellite instability (MSI), tandem repeats, and rare variant confirmation. 1,2

Download our latest infographic to:

  • Explore the benefits of using Sanger sequencing in diagnostic laboratories
  • Compare Sanger vs. NGS Sequencing for Clinical Decisions
  • Learn about the key features of QuantumSeq™ Sanger Sequencing Reagents and understand the competitor analysis

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